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Anti-14-3-3 alpha + beta Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | 14-3-3 protein beta/alpha |
Synonyms: | YWHAB, GW128, HEL-S-1, KCIP-1, YWHAA, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse 14-3-3 alpha + beta |
Uniprot ID: | Q9CQV8 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | colon, esophagus cancer, fetal rat |
Background
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
Images
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Immunohistochemistry of paraffin embedded human colon using 14-3-3 (GB12592) at dilution of 1: 1000 (380x lens) |
 | Immunohistochemistry of paraffin embedded human esophagus cancer using 14-3-3 (GB12592) at dilution of 1: 1000 (380x lens) |
 | Immunofluorescence of paraffin embedded human intestine cancer using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse fetal rat using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) |
 | Immunofluorescence of paraffin embedded rat colon using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded rat skin using 14-3-3α (GB12592) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
