Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | 53BP2/ASPP2/BBP rabbit polyclonal antibody |
Gene Name: | Apoptosis-stimulating of p53 protein 2 |
Synonyms: | Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, Aspp2, Trp53bp2, BBP, PPP1R13A |
Immunogen: | Recombinant protein corresponding to Mouse BBP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 125 kDa |
Observed MW. | 125 kDa |
Uniprot ID: | Q13625, Q8CG79 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, brain |
Background
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
Western blot analysis of ASPP2 (GB111947) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |