AAV CAG-Cre (30 µl)

AAV(PHP.S)-CAG-Cre is a pre-packaged rAAV in serotype PHP.S (with capsid from AAV serotype PHP.S and 2xITR from AAV serotype 2) which over-expresses Cre recombinase under CAG (also known as CBA) promoter. CAG promoter is a combination of the cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter for high levels of gene expression in mammalian expression vectors. Ready to use format.

rAAV serotype PHP.S, a newly identified artificial serotype, was proved to transduce peripheral nervous systems most efficiently. It was reported that 1x10^12 VG of AAV-PHP.S transduced 82% of dorsal root ganglion neurons while same dose of AAV serotype 9 failed to transduce.