AAV CAG-mCherry (30 µl)

AAV(BR1)-CAG-mCherry is a pre-packaged rAAV in serotype retrograde (with capsid from AAV serotype BR1 and 2xITR from AAV serotype 2) which over-expresses mCherry under CAG (also known as CBA) promoter. CAG promoter is a combination of the cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter for high levels of gene expression in mammalian expression vectors. Ready to use format.

AAV serotype BR1, a newly identified serotype from capsid AAV2 mutant has shown excellent transduction efficiency for neurovascular (blood–brain barrier‐associated) endothelial cells in vivo and in vitro. AAV‐BR1 can be used to ameliorate the severe neurological impairments in a mouse model of incontinentia pigmenti.