AAV CMV-Cre (30 µl)

AAV(PHP.S)-CMV-Cre is a pre-packaged rAAV in serotype PHP.S (with capsid from AAV serotype PHP.S and 2xITR from AAV serotype 2) which over-expresses Cre under CMV promoter. This pre-made rAAV is used in the Cre-lox system as a genetic tool to generate site-specific recombination of DNA between loxP sites in cultured cells and animal experiments. Ready to use format.

rAAV serotype PHP.S, a newly identified artificial serotype, was proved to transduce peripheral nervous systems most efficiently. It was reported that 1x10^12 VG of AAV-PHP.S transduced 82% of dorsal root ganglion neurons while same dose of AAV serotype 9 failed to transduce.