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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AC5 rabbit polyclonal antibody |
Gene Name: | Adenylate cyclase type 5 |
Synonyms: | ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5, Adcy5, AC5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AC5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | O95622 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 50-1: 200 | kidney |
Background
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Images
 | Immunohistochemistry of paraffin embedded human kidney using ADCY5-6 (GB112418) at dilution of 1:60 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
