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Anti-ACY-1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ACY-1 rabbit polyclonal antibody |
Gene Name: | Aminoacylase-1 |
Synonyms: | ACY-1, N-acyl-L-amino-acid amidohydrolase, Acy1, Acylase I, ACYLASE, HEL-S-5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ACY-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | Q99JW2 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney, brain, colon |
Background
Aminoacylase 1 is a cytosolic, homodimeric, zinc binding enzyme that catalyzes the hydrolysis of acylated L amino acids to L amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase 1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc binding enzymes.
Images
| Western blot analysis of Aminoacylase1 (GB112061) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
