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| Reactivity: | R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ADI1 rabbit polyclonal antibody |
Gene Name: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
Synonyms: | Acireductone dioxygenase (Fe(2+)-requiring), ARD, Fe-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1, Submergence-induced protein-like factor, Sip-L, MTCBP1, HMFT1638 |
Immunogen: | Recombinantproteincorrespondingto Human ADI1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Nucleus, Cytoplasm |
Uniprot ID: | Q562C9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 600-1: 3000 | heart, lung |
Background
ADI1(acireductone dioxygenase 1 ) is also named as SIPL, ARD, APL1, HMFT1638, MTCBP-1, FLJ10913, MTCBP1 and belongs to the acireductone dioxygenase (ARD) family. It catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).The downregulation of ADI1 protein expression in human prostate cancer specimens argues that ADI1 potentially inhibits the growth that occurs during prostate cancer progression(PMID:17786183). It has 2 isoforms produced by alternative splicing.
Images
| Immunohistochemistry of paraffin embedded rat heart using ADI1 (GB111667) at dilution of 1:1600 (300x lens) |
 | Immunofluorescence of paraffin embedded rat lung using ADI1 (GB111667) at dilution of 1:1200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
