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Anti-ADIPOR1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ADIPOR1 rabbit polyclonal antibody |
Gene Name: | Adiponectin receptor protein 1 |
Synonyms: | Progestin and adipoQ receptor family member 1, Adipor1, Parq1, TESBP1A |
Immunogen: | Recombinant protein corresponding to Mouse ADIPOR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | Q91VH1 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Mouse, Rat | 1:600-1:1200 | rectum |
Background
Acrp30 is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin resistance and diabetes. This insulin-sensitizing effect of adiponectin seems to be mediated by an increase in fatty-acid oxidation through activation of AMP kinase and PPAR- .
Images
| Immunohistochemistry of paraffin embedded mouse rectum using Adipor1 (GB112269) at dilution of 1:600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat rectum using Adipor1 (GB112269) at dilution of 1:600 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
