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| Reactivity: | Mouse |
| Applications: | FCM |
| Host Species: | Armenian Hamster |
| Isotype: | Armenian Hamster IgG |
| Clonality: | Monoclonal |
| Conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| Synonyms: | T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7 |
| Background: | CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Gene ID: | 12519 |
| SwissProt: | Q00609 |
| Concentration: | 0.5 mg/mL |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Storage: | Store at 2~8°C. Do not freeze. |
| Documents: | Please contact us to request the manual |
