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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AG-3 rabbit polyclonal antibody |
Gene Name: | Anterior gradient protein 3 |
Synonyms: | Agr3, AG3, Anterior gradient homolog 3, BCMP11, hAG 3, PDIA18, Protein disulfide isomerase family A member 18 |
Immunogen: | Recombinant protein corresponding to Mouse AG-3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q8TD06 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 600-1: 1500 | breast cancer, uterus |
Background
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
Images
| Immunofluorescence of paraffin embedded human breast cancer using AGR3 (GB111744) at dilution of 1:800 (300x lens) |
| Immunofluorescence of paraffin embedded human uterus using AGR3 (GB111744) at dilution of 1:800 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
