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Anti-ALDH1L1 Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
Synonyms: | 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, Aldh1l1, Fthfd, ALDH1L1 |
Immunogen: | Recombinant protein corresponding to Mouse ALDH1L1 |
Uniprot ID: | Q8R0Y6 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 99 kDa / 99 kDa |
Applications
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, kidney, liver, pancreas |
Background
Aldehyde dehydrogenase 1 family member L1 (ALDH1L1), belongs to the aldehyde dehydrogenase family of proteins and is responsible for formate oxidation in vivo. Loss of ALDH1L1 is associated with decreased apoptosis, increased cell motility, and cancer progression. ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Images
| Western blot analysis of ALDH1L1 (GB12665) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
