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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Adenylosuccinate lyase |
Synonyms: | Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AMPS |
Uniprot ID: | P54822 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 55 kDa / 50-55 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | brain, heart, skeletal muscle |
Background
Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
Images
| Western blot analysis of ADSL (GB114716) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
