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Anti-ANKK1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ANKK1 rabbit polyclonal antibody |
Gene Name: | Ankyrin repeat and protein kinase domain-containing protein 1 |
Synonyms: | Ankk1, X kinase, Sugen kinase 288, SGK288, Protein kinase PKK2, PKK2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ANKK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8NFD2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 100-1: 400 | colon, gastric cancer |
Background
ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Images
| Immunohistochemistry of paraffin embedded human colon using ANKK1 (GB112377) at dilution of 1:200 (400x lens) |
| Immunohistochemistry of paraffin embedded human gastric cancer using ANKK1 (GB112377) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
