Reactivity: | H,M,R & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member C |
Synonyms: | PP32R1, pp32 related 1, ANP32C, Tumorigenic protein pp32r1 |
Immunogen: | Recombinant protein corresponding to Human ANP32C/PP32R1 |
Uniprot ID: | O43423 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 27 kDa / 28 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | prostate, lymph node |
IHC/IF | Human | 1: 500-1: 1000 | endometrial carcinoma, kidney |
Background
The protein encoded by ANP32C is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene.
Images
Western blot analysis of ANP32C (GB114550) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human endometrial carcinoma using ANP32C (GB114550) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded human kidney using ANP32C (GB114550) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded human esophageal carcinoma using ANP32C (GB114550) at dilution of 1: 500 | |
Immunofluorescence analysis of paraffin embedded human kidney using ANP32C (GB114550) at dilution of 1: 500 | |
Immunofluorescence analysis of paraffin embedded human renal carcinoma using ANP32C (GB114550) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |