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Anti-AP-2 complex subunit alpha-1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ap2a1 rabbit polyclonal antibody |
Gene Name: | AP-2 complex subunit alpha-1 |
Synonyms: | 100 kDa coated vesicle protein A, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin A, Alpha1-adaptin, Ap2a1, Adtaa, Clapa1 |
Immunogen: | Recombinant protein corresponding to Mouse Ap2a1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 108 kDa |
Observed MW. | 108 kDa |
Uniprot ID: | O95782 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HEK293, HeLa, A-431 , 293T, HepG2 |
Background
AP2A1 encodes adaptor protein complex 2 (AP-2) subunit alpha-1, which is a 100 kDa coated vesicle protein. Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes also play a pivotal role in the cargo selection by recognizing the sorting signals within the cytoplasmic tail of integral membrane proteins. AP-2 is involved in clathrin-dependent endocytosis.
Images
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Western blot analysis of ap2a1 (GB111116) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
