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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | APC |
Synonyms: | CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1 |
Background: | CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
Gene ID: | 3820 |
SwissProt: | Q12918 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |