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| Reactivity: | Human |
| Applications: | FCM |
| Host Species: | Mouse |
| Isotype: | Mouse IgG2a, κ |
| Clonality: | Monoclonal |
| Conjugation: | APC |
| Synonyms: | FB22,Fusin,HM89,LCR1,LAP-3 |
| Background: | CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2. |
| Gene ID: | 7852 |
| SwissProt: | P61073 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
| Documents: | Please contact us to request the manual |
