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Reactivity: | Human |
Applications: | FCM |
Host Species: | Mouse |
Isotype: | Mouse IgG1, κ |
Clonality: | Monoclonal |
Conjugation: | APC |
Synonyms: | APT1,FAS1,TNFRSF6,Apo-1 antigen,FASLG receptor |
Background: | CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance. |
Gene ID: | 355 |
SwissProt: | P25445 |
Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
Documents: | Please contact us to request the manual |