Reactivity: | M & M |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Protein APCDD1 |
Synonyms: | B7323, DRAPC1, FP7019, HHS, HTS, hypoptrichosis simplex, Protein APCDD1 |
Immunogen: | Recombinant protein corresponding to Mouse APCDD1 |
Uniprot ID: | Q3U128 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 59 kDa / 59 kDa |
Product Usage Information
WB | Mouse | 1: 2000-1: 3000 | kidney |
IHC/IF | Mouse | 1: 700-1: 2100 | kideny, colon, skin |
Background
Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins (By similarity).
Images
Western blot analysis of APCDD1 (GB114520) at dilution of 1: 2000 | |
Immunohistochemistry of paraffin embedded mouse kideny using APCDD1 (GB114520) at dilution of 1: 700 | |
Immunohistochemistry of paraffin embedded mouse colon using APCDD1 (GB114520) at dilution of 1: 700 | |
Immunofluorescence of paraffin embedded mouse skin using APCDD1 (GB114520) at dilution of 1: 700 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |