Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | APOA4 rabbit polyclonal antibody |
Gene Name: | Apolipoprotein A-IV |
Synonyms: | Apo-AIV, ApoA-IV, Apolipoprotein A4, Apoa4, Apolipoprotein A IV |
Immunogen: | Recombinant protein corresponding to Mouse APOA4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P06728, P02651 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 2000 | small intestine |
Background
APOA4 is a major protein component of chylomicrons in postprandial lymph and plasma. It is synthesized in the small intestine and the liver, attached to chylomicrons by enterocytes, and secreted into intestinal lymph during fat absorption. APOA4 is intimately involved in metabolism and has protective roles in cardiovascular diseases like atherosclerosis. APOA4 can promote insulin secretion and maintain glucose homeostasis. It also has potent antioxidant and anti-inflammatory properties.
Images
Immunohistochemistry of paraffin embedded mouse small intestine using APOA4 (GB111436) at dilution of 1:1200 (300x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using APOA4 (GB111436) at dilution of 1:1200 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |