Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ATF-4 rabbit polyclonal antibody |
Gene Name: | Cyclic AMP-dependent transcription factor ATF-4 |
Synonyms: | cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, C/EBP-related ATF, C/ATF, TaxREB67 homolog, Atf4 |
Immunogen: | Recombinant protein corresponding to Mouse ATF-4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm, Nucleus |
Uniprot ID: | P18848, Q06507, Q9ES19 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:1500-1:3000 | bone, brain, breast cancer, colon, liver |
Background
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins.
Images
Immunohistochemistry of paraffin embedded human colon using ATF4 (GB111137) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse bone using ATF4 (GB111137) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using ATF4 (GB111137) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse liver using ATF4 (GB111137) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded rat liver using ATF4 (GB111137) at dilution of 1:1600 (400x lens) | |
Immunofluorescence of paraffin embedded human breast cancer using ATF4 (GB111137) at dilution of 1:1500 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |