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Anti-ATF2 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ATF2 rabbit polyclonal antibody |
Gene Name: | Cyclic AMP-dependent transcription factor ATF-2 |
Synonyms: | ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATF2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Mitochondrion outer membrane |
Uniprot ID: | P16951, Q00969 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:500-1:1000 | brain |
Background
A transcription factor that is a member of the leucine zipper family of DNA binding proteins. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Images
| Immunohistochemistry of paraffin embedded mouse brain using ATF2 (GB11315-1) at dilution of 1:500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using ATF2 (GB11315-1) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using ATF2 (GB11315-1) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
