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Anti-ATP9A Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Probable phospholipid-transporting ATPase IIA |
Synonyms: | ATP9A, ATPase class II type 9A, ATPase, class II, type 9A, ATPIIA, KIAA0611 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATP9A |
Uniprot ID: | O70228 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 119 kDa / 105(H),119(M) kDa |
Product Usage Information
WB | Human, Mouse | 1: 1000-1: 2000 | testis, skeletal muscle |
Background
Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling and endosome to trans-Golgi network retrograde transport. In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation. Appears to be implicated in intercellular communication by negatively regulating the release of exosomes. The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved.
Images
| Western blot analysis of ATP9A (GB114859) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
