Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Acetylcholinesterase rabbit polyclonal antibody |
Gene Name: | Acetylcholinesterase |
Synonyms: | AchE, acetylhydrolase, acetylcholinesterase ACEE, ARN-YT, acetylcholinesterase, AChE |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AchE |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secreted, Synapse |
Uniprot ID: | P22303, P21836, P37136 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 2000 | brain, prefrontal lobe, spinal cord |
Background
Acetylcholinesterase, also known as AchE or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AchE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Images
Immunohistochemistry of paraffin embedded mouse brain using ACHE (GB11038-1) at dilution of 1:400 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse prefrontal lobe using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse spinal cord using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using ACHE (GB11038-1) at dilution of 1:400 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spinal cord using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded mouse prefrontal lobe using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spinal cord using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using ACHE (GB11038-1) at dilution of 1:800 (400x lens) | |
Immunofluorescence of paraffin embedded rat spinal cord using ACHE (GB11038-1) at dilution of 1:800 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |