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Anti-Acetylcholinesterase Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Acetylcholinesterase rabbit polyclonal antibody |
Gene Name: | Acetylcholinesterase |
Synonyms: | ACHE, ACEE, ARACHE, YT blood group, N-ACHE, Acetylcholine acetylhydrolase, Apoptosis related acetylcholinesterase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Acetylcholinesterase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 68 kDa |
Observed MW. | 68 kDa |
Uniprot ID: | P22303, P21836, P37136 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, brain, cerebellum |
Background
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
Images
| Western blot analysis of ACHE (GB112056) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
