Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Acinus rabbit polyclonal antibody |
Gene Name: | Apoptotic chromatin condensation inducer in the nucleus |
Synonyms: | Acin1, ACIN1, ACINUS, ACN, fSAP152, apoptotic chromatin condensation inducer 1 |
Immunogen: | Recombinant protein corresponding to Mouse Acinus |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 151 kDa |
Observed MW. | 151 kDa |
Uniprot ID: | Q9UKV3 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1:500-1:1000 | Jurkat, K562, Hela |
Background
Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
Images
Western blot analysis of Acinus (GB11786) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |