Product Category:
Human Adenovirus Type5 (dE1/E3) expressing ABCC8.
Description:
ATP-binding Cassette, Sub-family C (CFTR/MRP), Member 8, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
ATP-binding Cassette, Sub-family C (CFTR/MRP), Member 8
ACCN:
NM_000352.3
Gene ID:
6833
GI Number:
6833
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by ABCC8 gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release.
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