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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Angiotensin II Receptor, Type 1 (AGTR1). |
| Description: | Angiotensin II Receptor, Type 1, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Angiotensin II Receptor, Type 1 |
| NCBI Acc. #: | BC022447 |
| Gene ID: | 185 |
| GI Number: | 185 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. |
| Documents: | Please contact us to request the manual |
