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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Angiopoietin 1 (ANGPT1) under a CMV promoter. |
| Description: | Angiopoietin 1, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Angiopoietin 1 |
| NCBI Acc. #: | BX648814.1 |
| Gene ID: | 284 |
| GI Number: | 34367979 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | ANGPT1 gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Documents: | Please contact us to request the manual |
