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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing human Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein). |
| Description: | Pre-made adenovirus for over-expression of human Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein), ready to ship and ready to use format. |
| Gene: | Beclin 1 (coiled-coil, Myosin-like BCL2 Interacting Protein) |
| NCBI Acc. #: | BC010276 |
| Gene ID: | 8678 |
| GI Number: | 16307456 |
| Fusion Tag: | C-terminus V5 tag |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Beclin 1 (BECN1) plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |
