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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Bone Morphogenetic Protein 2 (BMP2) under a CMV promoter.
Description:
Bone Morphogenetic Protein 2, pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Bone Morphogenetic Protein 2
ACCN:
NM_001200
Gene ID:
650
GI Number:
80861484
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Bone morphogenetic protein-2 (BMP2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
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