Your shopping cart is empty!
Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related under a CMV promoter.
Description:
Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related, pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related
ACCN:
BC005850
Gene ID:
862
GI Number:
13543377
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
CBFA2T1 gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Documents:
