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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing CCAAT/enhancer Binding Protein (C/EBP), Alpha (CEBPA).
Description:
CCAAT/enhancer Binding Protein (C/EBP), Alpha, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
CCAAT/enhancer Binding Protein (C/EBP), Alpha
ACCN:
NM_004364.2
Gene ID:
1050
GI Number:
28872793
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1011~1x1012 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by CEBPA gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
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