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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Carnitine Palmitoyltransferase 1A (liver) (CPT1A) under a CMV promoter. |
| Description: | Carnitine Palmitoyltransferase 1A (liver), pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Carnitine Palmitoyltransferase 1A (liver) |
| NCBI Acc. #: | BC000185 |
| Gene ID: | 1374 |
| GI Number: | 12652864 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Documents: | Please contact us to request the manual |
