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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Endoglin (Osler-Rendu-Weber Syndrome 1), under CMV promoter. |
| Description: | Endoglin (Osler-Rendu-Weber Syndrome 1), pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Endoglin (Osler-Rendu-Weber Syndrome 1) |
| NCBI Acc. #: | BC014271 |
| Gene ID: | 2022 |
| GI Number: | 2022 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. |
| Documents: | Please contact us to request the manual |
