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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing FOS-like Antigen 1 (FOSL1) gene under CMV promoter.
Description:
FOS-like Antigen 1, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
FOS-like Antigen 1
ACCN:
NM_005438
Gene ID:
8061
GI Number:
4885242
Fusion Tag:
No
Promoter:
CMV
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
Documents:
