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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Hepatocyte Growth Factor (hepapoietin A; Scatter Factor) (HGF). |
| Description: | Hepatocyte Growth Factor (hepapoietin A; Scatter Factor), pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Hepatocyte Growth Factor (hepapoietin A; Scatter Factor) |
| NCBI Acc. #: | M73239 |
| Gene ID: | 3082 |
| GI Number: | 337935 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Hepatocyte growth factor （HGF） regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. |
| Documents: | Please contact us to request the manual |
