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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Hypoxia-inducible Factor 1, Alpha Subunit (basic Helix-loop-helix Transcription Factor) (HIF1A).
Description:
Hypoxia-inducible Factor 1, Alpha Subunit (basic Helix-loop-helix Transcription Factor), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Hypoxia-inducible Factor 1, Alpha Subunit (basic Helix-loop-helix Transcription Factor)
ACCN:
BC012527
Gene ID:
3091
GI Number:
15214787
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
HIF1A gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.
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