Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Insulin-like Growth Factor 2 (somatomedin A) under CMV promoter.
Description:
Insulin-like Growth Factor 2 (somatomedin A), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Insulin-like Growth Factor 2 (somatomedin A)
ACCN:
BC000531
Gene ID:
3481
GI Number:
12653518
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
IGF2 gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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