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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing human Integrin, Alpha 1. |
| Description: | Pre-made adenovirus for over-expression of human Integrin, Alpha 1, ready to ship and ready to use format. |
| Gene: | Integrin, Alpha 1 |
| NCBI Acc. #: | NM_001033228.3 |
| Gene ID: | 3672 |
| GI Number: | 153791388 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |
