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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing mouse Potassium channel subfamily K member 2. |
| Description: | Pre-made adenovirus for over-expression of mouse Potassium channel subfamily K member 2; Ready to ship and ready to use format. |
| Gene: | Potassium channel subfamily K member 2 |
| NCBI Acc. #: | NM_001159850.1 |
| Gene ID: | 16526 |
| GI Number: | 16526 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants. |
| Documents: | Please contact us to request the manual |
