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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Lysyl Oxidase-like 2 (LOXL2) under a CMV promoter. |
Description: | Lysyl Oxidase-like 2,pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Lysyl Oxidase-like 2 |
NCBI Acc. #: | BC000594 |
Gene ID: | 4017 |
GI Number: | 12653632 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1011~1x1012 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | The LOXL2 gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. |
Documents: | Please contact us to request the manual |