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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2). |
| Description: | Nuclear Receptor Subfamily 4, Group A, Member 2, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Nuclear Receptor Subfamily 4, Group A, Member 2 |
| NCBI Acc. #: | BC009288.2 |
| Gene ID: | 4929 |
| GI Number: | 33874453 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The Nuclear receptor related 1 protein (Nurr1) also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2) is a protein that in humans is encoded by the NR4A2 gene. NURR1 is a member of the nuclear receptor family of intracellular transcription factors.Nurr1 plays a key role in the maintenance of the dopaminergic system of the brain. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's disease, schizophrenia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full-length nature has not been determined. |
| Documents: | Please contact us to request the manual |
