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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Osteoglycin (OGN) under a CMV promoter.
Description:
Osteoglycin (osteoinductive Factor, Mimecan), pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Osteoglycin (osteoinductive Factor, Mimecan)
ACCN:
AL110267
Gene ID:
4969
GI Number:
5817232
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.
Documents:
