Your shopping cart is empty!
Product Category:
Human Adenovirus Type5 (dE1/E3) expressing OLIG2.
Description:
This recombinant human adenovirus type 5 (dE1/E3) expresses human oligodendrocyte lineage transcription factor 2 (OLIG2) with mCherry co-expression under a separate CMV promoter.
Gene Name:
Oligodendrocyte lineage transcription factor 2
ACCN:
BC047511
Gene ID:
10215
GI Number:
28704079
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
OLIG2 gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Documents:
