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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Poly (ADP-ribose) Polymerase Family, Member 1 (PARP1) under a CMV promoter. |
| Description: | Poly (ADP-ribose) Polymerase Family, Member 1, pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Poly (ADP-ribose) Polymerase Family, Member 1 |
| NCBI Acc. #: | BC037545 |
| Gene ID: | 142 |
| GI Number: | 22902365 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species. |
| Documents: | Please contact us to request the manual |
