Adenovirus PDPK1-DN (200 µl)

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing 3-phosphoinositide Dependent Protein Kinase-1 (kinase dead or dominant negative), under CMV promoter.

Description:

3-phosphoinositide Dependent Protein Kinase-1 (kinase dead or dominant negative), premade adenovirus, ready to ship and ready to use format.

Gene Name:

3-phosphoinositide Dependent Protein Kinase-1 (kinase dead or dominant negative)

ACCN:

BC012103

Gene ID:

5170

GI Number:

15082378

Fusion Tag:

C-terminus 6xHN tag

Promoter:

CMV

Titer:

1E+10~1E+11 PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Documents:

Request a manual/MSDS