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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Prolactin Receptor under CMV promoter.
Description:
Prolactin Receptor, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Prolactin Receptor
ACCN:
M31661
Gene ID:
5618
GI Number:
5618
Fusion Tag:
No
Promoter:
CMV
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Prolactin (PRL) is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor (PRLR), a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. PRLR consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.
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