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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing PRas Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 under CMV promoter. |
| Description: | Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 |
| NCBI Acc. #: | BC030021.1 |
| Gene ID: | 11228 |
| GI Number: | 20988633 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Documents: | Please contact us to request the manual |
