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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing PRas Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 under CMV promoter.
Description:
Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8
ACCN:
BC030021.1
Gene ID:
11228
GI Number:
20988633
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents:
